Pregnal (HCG) 5000iu Vial
HCG – Human Chorionic Gonadotropin 5000iu is a synthetic form of the hormone produced by the placenta during pregnancy, but when used in men, it acts as a luteinizing hormone (LH) analog. LH signals the testes to produce testosterone, making HCG extremely effective for men experiencing suppressed testosterone levels due to anabolic steroid use or other medical conditions.
In bodybuilding and TRT protocols, HCG is used to maintain or restore testicular function and size during and after steroid cycles. It plays a critical role in post-cycle therapy (PCT) and is also used by men trying to preserve fertility during extended periods of performance-enhancing drug use.
By mimicking LH, HCG helps stimulate natural testosterone production, maintain libido, and support sperm production. When used appropriately, it can prevent shutdown of the hypothalamic-pituitary-gonadal (HPG) axis and maintain hormonal balance.
Benefits
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Stimulates natural testosterone production
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Maintains testicular size and function during steroid cycles
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Supports fertility and sperm production
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Prevents complete shutdown of the HPG axis
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Helps restore hormonal balance during PCT
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Enhances libido and mood
Side effects
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Estrogenic side effects: water retention, gynecomastia (when aromatization increases)
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Acne or oily skin
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Headaches or mood swings
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Injection site irritation
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Risk of desensitization of Leydig cells if used chronically or in high doses
Dosages & Protocol
For Men
During Cycle (as on-cycle support):
Beginner: 250iu twice per week = 500iu/week
Intermediate: 500iu twice per week = 1000iu/week
Advanced: 500iu 3x/week = 1500iu/week
Used to maintain testicular function and prevent shutdown
For PCT (Post-Cycle Therapy):
Typical dose: 1000iu every other day for 10 days (total of 5,000iu)
Alternatively: 500iu daily for 10 days
HCG should be followed by a SERM (like Clomid or Nolvadex) to complete recovery protocol.
PLEASE MAKE USE OF OUR PEPTIDE CALCULATOR FOR FURTHER DOSAGE GUIDANCE.
Not recommended for women due to high chance of virilization.
How to administer
Administering HCG – Human Chorionic Gonadotropin requires reconstitution and proper subcutaneous or intramuscular injection technique.
Reconstitution Instructions:
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Using a sterile syringe, slowly inject 2ml of bacteriostatic water into the lyophilized HCG vial.
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Swirl gently (do not shake) until completely dissolved.
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Store the reconstituted solution in the refrigerator and use within 30 days.
Injection Instructions:
Gather Supplies:
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Reconstituted HCG solution
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1ml insulin syringe (for subcutaneous use)
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Alcohol swabs
Prepare the Injection Site:
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Wash your hands thoroughly
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Choose a subcutaneous injection site (lower abdomen or thigh)
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Clean the area with an alcohol swab
Prepare the Syringe:
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Draw the required dose into the insulin syringe (e.g., 0.1ml = 250iu if 5000iu reconstituted in 2ml)
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Tap to remove any air bubbles
Administer the Injection:
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Pinch the skin at the site
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Insert the needle at a 45-degree angle
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Inject the solution slowly
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Withdraw the needle and apply light pressure with an alcohol swab
Post-Injection Care:
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Dispose of used needle safely
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Store remaining solution in the refrigerator
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Monitor for any irritation or side effects
Storage
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Store lyophilized powder in a cool, dry place before mixing
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After reconstitution, store at 2–8°C (refrigerator)
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Use within 30 days
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Protect from light
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Keep out of reach of children
Half-life & detectability
Half-life: Approximately 36 hours
Detection time: Up to 7–10 days depending on testing method
For athletes subject to drug testing, it is important to consider these detection times and plan accordingly to avoid positive tests for banned substances.
Dosage Instructions
2500iu -7500iu’s per week via subcutaneous abdominal injection with a typical cycle length of 4-6 Weeks.
Whichever purpose you are using HCG for – on cycle or for PCT – the dosage and administration of this hormone is very sparse and controlled and unlike that of any other compound you will be using whether that be steroids themselves or drugs like SERMs and AIs.
When buying HCG from your chosen source you will normally receive a small packet of powder containing the active ingredients and another with sterile water in it. These two items are to be mixed to form your injectable ingredient. Any leftover must be refrigerated for later use – do not store the solution at room temperature.
HCG Dosage During Anabolic Steroid Use
When using HCG during your steroid cycle you will want to take it no more than once every 3 to 5 days at a maximum. This will come as some relief since HCG is an injection, so you won’t have to be adding an extra injection to your steroid program too often.
A very low dose of HCG during this time is considered sufficient and this is usually in the realm of 250iu. There is no benefit to increasing the dose beyond this level, nor the frequency of administration.
This modest dosage is enough to give you all the benefits you want from HCG without putting your future testosterone restoration at risk by having the body become dependent on HCG which is an increased risk when you increase the dose – therefore, 250iu once every 5 days is suitable for most male steroid users while on cycle.
HCG Dosage for Increased Endogenous Testosterone Secretion and PCT
HCG is most used as a kick start to your PCT cycle in preparation for the use of SERMs afterwards. The length and dose of HCG during this time should be determined on how powerful your steroid cycle was and the level of testosterone suppression it is likely to have caused.
This can be difficult for new steroid users to gauge initially so a lower HCG dose is advised in those circumstances.
Many users will take HCG for a period of two to three weeks with doses every 3 or 4 days starting at 1000iu at the low end right up to 4000iu. This higher dosage is advised only for advanced users who have used HCG previously and understand its effects. Following this short HCG cycle, SERM administration can begin to carry through the rest of your PCT phase.
Effect on Cycle
HCG & STEROIDS:
For steroid users who make use of HCG while using anabolic steroids the intent is to use this hormone to address the suppression of natural hormones that takes place when you use most types of steroids.
During this time your normal testosterone production and levels will be extremely low or even non-existent and the use of HCG during steroid use can prevent the problem of testicular atrophy but more importantly, taking HCG during a steroid cycle helps prime the body for recovery once your cycle ends.
So, what’s the downside to HCG and why doesn’t everyone just use it during a cycle? One of the commonly overlooked issues is the way the male body can become dependent on HCG’s supply of what is basically exogenous luteinizing hormone. Guys who take too much HCG or don’t seriously regulate use of it are at higher risk of dependence.
Those men who go overboard with their use of HCG during a steroid cycle, either through lack of knowledge or a false belief that more equals better, can quickly find themself suffering with a low testosterone condition. Those who know how to use HCG responsibly during a steroid cycle however will reap the benefits and avoid the problem of dependence occurring.
HCG VS AROMATASE INHIBITORS VS SERMs
HCG is very different from both SERMs and aromatase inhibitors (AIs).
Both SERMs and AIs are medications that have been designed to either block specific estrogen receptors (in the case of SERMs), or to lower overall estrogen levels (AIs). HCG on the other hand is a naturally occurring hormone produced in women once they fall pregnant.
HCG does not target estrogen in any way, but instead is able to directly help stimulate testosterone in men because it works in a very similar way to luteinizing hormone.
Both SERMs and AIs are mainly used to treat breast cancer in women. HCG is used medically to treat low testosterone and infertility and men, as well as fertility problems in women. All three categories of substances are therefore available with a prescription. While both SERMs and AIs are available as different products with slightly differing chemical structures and effects between them, HCG is the only one of the three that is a single hormone with no variation between products.
HCG is available in injection form only, while AI and SERM drugs are oral tablets that need to be taken more regularly than the once or twice weekly injections that HCG is normally administered by.
HCG is not intended to replace either SERMs or AIs at any point during or after a steroid cycle. Instead, it can be a very useful addition but one that needs to be used carefully and with knowledge of both how to dose it properly and what it can and can’t do both in benefits and side effects. Over-use of HCG can have the opposite of your intended effect: instead of improving or restoring your testosterone you could find yourself back in a low testosterone state.
HCG FOR POST CYCLE THERAPHY:
Post cycle therapy use of HCG is the most common reason guys will use this hormone for the purpose of optimizing recovery after a steroid cycle. The power of this hormone for PCT use comes with taking it before starting a SERM cycle.
Most PCT plans will include either or both SERMs Nolvadex (Tamoxifen Citrate) and Clomid (Clomiphene Citrate) and while these are generally very effective on their own, many steroid users find that adding HCG to the PCT phase provides enhanced recovery benefits.
The strategy here is to make use of HCG prior to starting your regular SERM dosage, with HCG essentially acting as a kick start to the hormone production process thanks to the way it mimics luteinizing hormone. The SERMs then take over for the rest of your PCT cycle, providing a more efficient and effective recovery.
This type of PCT plan provides for the two main purposes of post cycle therapy: to help you maintain your gains and to speed up the restart of natural testosterone production; this hormone will be in a greatly suppressed state at the end of your steroid cycle in most cases and without a proper PCT plan the rate of recovery is extremely slow which puts you in the certain position of low testosterone and the associated symptoms and muscle loss.
HCG will usually be started within a 4-to-6-week period after the end of your steroid cycle, but the timing will depend on the steroid compounds you’ve used. Those who are concerned about possible estrogenic side effects from using HCG during PCT, because of increased aromatase activity, might also choose to include an aromatase inhibitor into their PCT plan.
This is not always an effective idea because AIs come with their own set of issues when it comes to potentially negatively impacting on testosterone levels because of powerful estrogen suppression; in general, HCG is utilized for a short time frame during PCT, so side effects are not a great concern for most users.
Side Effects
One of the great positive about HCG is that side effects are rare to non-existent. Unlike other substances used by steroid users like SERMs and AIs, HCG is not a drug developed in a lab but instead is a naturally occurring hormone. This means we don’t have to worry about adverse effects like headaches, upset stomach or other common problems that come about with the use of powerful medications.
HCG can raise testosterone levels so the main effects to watch out for relate to rising levels of the hormone and these can come in the form of an estrogenic nature. Water retention and gynecomastia are possible but are considered rare particularly because HCG is not often used on its own but instead combined with anti-estrogen drugs that will themselves mitigate these side effects when you are on a steroid cycle.
Because of the increase in circulating testosterone and DHT, androgenic side effects can be a concern, and this might include increased oily skin and acne, increased body hair growth, and hair loss on the head but the risk of these adverse effects is highly individual and usually only affect men who are genetically predisposed to them, in the same way that androgenic side effects come about from steroid use.
With the use of HCG during post cycle therapy you are likely to be using it at higher doses, this is balanced by the fact that your use of HCG is also likely to be only for a short period of time so the risk of side effects during PCT is again quite low. All of these factors make HCG a hormone that is unlikely to cause you many or any problems at all and possibly is the most side effect friendly substance you will take at any time of anabolic steroid use.
The greatest risk with HCG is not in the form of traditional types of side effects that we see with steroids or other drugs, but rather whether the body starts becoming dependent on the external form of luteinizing hormone that you’re consuming.
When this happens, you will have the reverse effect occur – instead of testosterone levels rising or maintaining at a healthy level with the help of HCG, you’ll be back down to low testosterone because the testicles have become reliant on the amount of HCG you’re taking in. This is avoided with low dosing and only using HCG for a minimal period of time.
Below are some side effects you might experience:
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Pelvic pain
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Swelling of the hands or legs
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Stomach pain and swelling
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Shortness of breath
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Weight gain
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Diarrhea
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Nausea or vomiting
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Urinating less than normal